What causes chronic kidney disease?
Posted by Niemir Skałecki
as with all chronic diseases, the cause is simply not known
Posted by Zsa*Zsa* Galore
Although chronic kidney disease sometimes results from primary diseases of the kidneys themselves, the major causes are diabetes and high blood pressure.
Type 1 and type 2 diabetes mellitus cause a condition called diabetic nephropathy, which is the leading cause of kidney disease in the United States.
High blood pressure (hypertension), if not controlled, can damage the kidneys over time.
Glomerulonephritis is the inflammation and damage of the filtration system of the kidneys and can cause kidney failure. Postinfectious conditions and lupus are among the many causes of glomerulonephritis.
Polycystic kidney disease is an example of a hereditary cause of chronic kidney disease wherein both kidneys have multiple cysts.
Use of analgesics such as acetaminophen (Tylenol) and ibuprofen (Motrin, Advil) regularly over long durations of time can cause analgesic nephropathy, another cause of kidney disease. Certain other medications can also damage the kidneys.
Clogging and hardening of the arteries (atherosclerosis) leading to the kidneys causes a condition called ischemic nephropathy, which is another cause of progressive kidney damage.
Obstruction of the flow of urine by stones, an enlarged prostate, strictures (narrowings), or cancers may also cause kidney disease.
Other causes of chronic kidney disease include HIV infection, sickle cell disease, heroin abuse, amyloidosis, kidney stones, chronic kidney infections, and certain cancers.
If you have any of the following conditions, you are at higher-than-normal risk of developing chronic renal disease. Your kidney functions may need to be monitored regularly.
1.Diabetes mellitus type 1 or 2
2.High blood pressure
3.High cholesterol
4.Heart disease
5.Liver disease
6.Prior Kidney disease
7.Amyloidosis
8.Sickle cell disease
9.Systemic Lupus erythematosus
10.Vascular diseases such as arteritis, vasculitis, or fibromuscular dysplasia
11.Vesicoureteral reflux (a urinary tract problem in which urine travels the wrong way)
12.Problems of the joints or muscles that require regular use of anti-inflammatory medications
13.If you have a family history of kidney disease.
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For more info check out the National Kidney Foundation site:
http://www.kidney.org/kidneydisease/ckd/index.cfm#whatis
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Study Investigates Possible Cause of Kidney Disease associated with Chronic Reflux
A new study conducted by researchers in The Center for Clinical and Translational Research at The Research Institute at Nationwide Children's Hospital may help identify a genetic link in Vesicoureteral Reflux (VUR), a condition that can lead to chronic kidney disease in children. David Hains, MD, a pediatric nephrologist and researcher at Nationwide Children's, discusses the study's findings.
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