what is the most common extra-renal manifestation of adult polycystic kidney disease?
Posted by Nick N
Localized swelling, peritonitis, and hematuria are good indicators, but as far as extra-renal, the only signs I'm aware of are hypertension and gastroesophageal reflux.
Posted by Benevolo
The most common extra-renal manifestation of APKD is having multiple asymptomatic hepatic cysts, which occurs in up to 1/3 of patients. Another interesting finding in 25% is mitral valve prolapse. Even though they love to quiz on it, berry / cerebral aneurysms only occur in about 10% of patients, and I believe that link is solely due to the fact that they usually have chronic hypertension from their disease.
Posted by greydoc6
Without looking it up for the first time in 10 years, I will say hypertension.
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