Should a patient with non-functioning kidneys (removed due to failed transplant) take baclofen?Twitching and spasms, diminished mental capacity, repetitive talking of nonsense started after three doses of baclofen. Sounds like some of the serious side effects. Patient is on dialysis because of zero kidney function.
Twitching and spasms, diminished mental capacity, repetitive talking of nonsense started after three doses of baclofen. Sounds like some of the serious side effects. Patient is on dialysis because of zero kidney function. Stopped using the drug after the 3 doses and symptoms are slowly getting better. It seems like the conditions were the worst approximately 12 - 24 hours after the last dose was taken.
Posted by Randall
Sounds like they need to stop using it.
Posted by SZO
Baclofen is a medication used for spasticity that is often excreted by the kidneys. However, if there is a problem with the kidneys, there may be adverse reactions or even symptoms of overdose since it cannot be excreted in the kidneys. This may be a reason why it is contraindicated in patients with this condition.
Symptoms of overdose include seizures, drowsiness, dizziness, mental confusion, nausea, muscle weakness, trouble breathing.
Orignal From: Kidney Disease: Should a patient with non-functioning kidneys (removed due to failed transplant) take baclofen?
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